期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 7, 期 22, 页码 4598-4603出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b912400d
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资金
- Swiss National Science foundation
- COST [CM0703]
- EPFL
A dynamic combinatorial library of metal-dye complexes was obtained by reacting aqueous solutions of the dyes Methyl Calcein Blue, Arsenazo I, and Xylenol Orange with CuCl2 and NiCl2. The mixture gave a characteristic UV-Vis response upon addition of the peptide hormones angiotensin I and angiotensin II. This allowed distinguishing pure samples of peptide hormones from mixtures. The discriminatory power of the sensor was enhanced when the several UV/Vis measurements were performed during the equilibration process of the library.
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