期刊
OPTOMETRY AND VISION SCIENCE
卷 87, 期 12, 页码 930-941出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/OPX.0b013e3181ff9a8b
关键词
imaging; adaptive optics; retina; pathology; photoreceptors
资金
- Research to Prevent Blindness
- Foundation Fighting Blindness
- National Eye Institute, National Institute of Health [T32EY014537, R01EY017607, EY002162, R01EY014375 BRP]
- That Man May See, Inc.
- Bernard Newcomb Macular Degeneration Fund
- Hope for Vision
- Research to Prevent Blindness (Medical College of Wisconsin, UCSF Department of Ophthalmology)
The human retina is a uniquely accessible tissue. Tools like scanning laser ophthalmoscopy and spectral domain-optical coherence tomography provide clinicians with remarkably clear pictures of the living retina. Although the anterior optics of the eye permit such non-invasive visualization of the retina and associated pathology, the same optics induce significant aberrations that obviate cellular-resolution imaging in most cases. Adaptive optics (AO) imaging systems use active optical elements to compensate for aberrations in the optical path between the object and the camera. When applied to the human eye, AO allows direct visualization of individual rod and cone photoreceptor cells, retinal pigment epithelium cells, and white blood cells. AO imaging has changed the way vision scientists and ophthalmologists see the retina, helping to clarify our understanding of retinal structure, function, and the etiology of various retinal pathologies. Here, we review some of the advances that were made possible with AO imaging of the human retina and discuss applications and future prospects for clinical imaging. (Optom Vis Sci 2010;87:930-941)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据