期刊
OPTICS LETTERS
卷 36, 期 5, 页码 597-599出版社
OPTICAL SOC AMER
DOI: 10.1364/OL.36.000597
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资金
- Dutch Technology Foundation (STW) [STW 10040]
We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. The data was obtained from two fresh human coronary arteries ex vivo, showing different stages of disease. A 1.25mm diameter intravascular imaging catheter was built, comprising an angle-polished optical fiber adjacent to a 30MHz ultrasound transducer. Specific photoacoustic imaging of lipid content, a key factor in vulnerable plaques that may lead to myocardial infarction, is achieved by spectroscopic imaging at different wavelengths between 1180 and 1230 nm. Simultaneous imaging with intravascular ultrasound was performed. (C) 2011 Optical Society of America
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