Simultaneous recovery of tissue physiological and acoustic properties and the criteria for wavelength selection in multispectral photoacoustic tomography

We present an algorithm to directly reconstruct chromophore concentrations and acoustic velocity by multispectral photoacoustic tomography. We also derive the criterions to minimize the cross talk for simultaneous recovery of chromophore concentrations and acoustic velocity using multispectral photoacoustic data. We found that the image quality and the separation between acoustic velocity and different chromophore concentrations strongly depend on the measurement wavelengths of incident laser source. 0 2009 Optical Society of America