期刊
OPTICS LETTERS
卷 34, 期 20, 页码 3086-3088出版社
OPTICAL SOC AMER
DOI: 10.1364/OL.34.003086
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资金
- National Institutes of Health (NIH) [R01-NS057476, P01NS055104, P50NS010828, K99NS067050, R01-CA07528912]
- Air Force Office of Scientific Research (AFOSR) [FA9550-07-1-0014]
- Medical Free-Electron Laser Program [FA9550-07-1-0101]
We describe depth-resolved microscopy of cortical hemodynamics with high-speed spectral/Fourier domain optical coherence tomography (OCT). Stimulus-evoked changes in blood vessel diameter, flow, and total hemoglobin were measured in the rat somatosensory cortex. The results show OCT measurements of hemodynamic changes during functional activation and represent an important step toward understanding functional hyperemia at the microscopic level. (C) 2009 Optical Society of America
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