4.6 Article

Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation

期刊

OPTICS LETTERS
卷 33, 期 21, 页码 2556-2558

出版社

OPTICAL SOC AMER
DOI: 10.1364/OL.33.002556

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资金

  1. German Research Foundation (DFG) [HU 1006/2-1]
  2. European Union (EU) [FP7 HEALTH, 201880]
  3. National Institutes of Health (NIH) [R01-CA75289-09, R01-EY11289-20]
  4. Air Force Office of Scientific Research [FA9550-071-0014, FA9550-07-1-0101]

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We demonstrate en face swept source optical coherence tomography (ss-OCT) without requiring a Fourier transformation step. The electronic optical coherence tomography (OCT) interference signal from a h-space linear Fourier domain mode-locked laser is mixed with an adjustable local oscillator, yielding the analytic reflectance signal from one image depth for each frequency sweep of the laser. Furthermore, a method for arbitrarily shaping the spectral intensity profile of the laser is presented, without requiring the step of numerical apodization. In combination, these two techniques enable sampling of the in-phase and quadrature signal with a slow analog-to-digital converter and allow for real-time display of en face projections even for highest axial scan rates. Image data generated with this technique is compared to en face images extracted from a three-dimensional OCT data set. This technique can allow for real-time visualization of arbitrarily oriented en face planes for the purpose of alignment, registration, or operator-guided survey scans while simultaneously maintaining the full capability of high-speed volumetric ss-OCT functionality. (C) 2008 Optical Society of America

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