期刊
OPTICS EXPRESS
卷 16, 期 25, 页码 20597-20602出版社
OPTICAL SOC AMER
DOI: 10.1364/OE.16.020597
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We present an experimental and theoretical study of a new scheme for Near-Field Fluorescence Correlation Spectroscopy that, using the field enhancement by optical nanoantennas, allows the reduction of the observation volume 4 orders of magnitude below the diffraction limit. This reduction can be used in two different ways: to increase the sample concentration and to improve the spatial resolution of the dynamics under study. Our experimental results using individual gold nanoparticles and a 150 mu M Rose Bengal solution in glycerol confirm the volume reduction. (C) 2008 Optical Society of America
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