Visible-light-mediated photocatalytic difluoroalkylation/1,2-carbon migration sequences: synthesis of difluoroalkyl-substituted cyclic ketones

A visible-light-mediated photocatalytic ethoxycarbonyldifluoromethylation/1,2-carbon migration of alkenols is described. This approach provides a mild and operationally simple access to the synthesis of difluoralkyl-substituted cyclic ketones via difluoralkylation and 1,2-carbon migration of 1-(1-arylvinyl) cyclobutanol derivatives. (C) 2015 Published by Elsevier Ltd.