4.4 Article

Facile synthesis of trifluoroethyl aryl ethers through copper-catalyzed coupling of CF3CH2OH with aryl- and heteroaryl boronic acids

期刊

TETRAHEDRON LETTERS
卷 56, 期 33, 页码 4815-4818

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.06.066

关键词

Trifluoroethyl aryl ether derivatives; Chan-Lam coupling reaction; Arylboronic acids

资金

  1. Natural Science Foundation of China [20772114, 21172200]
  2. Research Program of Fundamental and Advanced Technology of Henan Province [122300413203]
  3. Technology Research and Development Funds of Zhengzhou [141PRCYY516]

向作者/读者索取更多资源

An efficient copper-catalyzed Chan-Lam reaction of trifluoroethanol with a variety of aryl- and heteroaryl boronic acids has been developed. This research provides a practical method to synthesize trifluoroethyl aryl ethers in moderate to good yields under mild conditions. (C) 2015 Published by Elsevier Ltd.

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