4.4 Article

Catalyst-free synthesis of N-β-hydroxyethyl pyrroles and indoles via a domino [3+2] cycloaddition and ring-opening aromatization process

期刊

TETRAHEDRON LETTERS
卷 56, 期 22, 页码 2913-2916

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.04.074

关键词

Catalyst-free; Cycloaddition; Ring-opening aromatization; Domino reaction

资金

  1. National Key Technology RD Program [2011BAE06B05-4]
  2. Shanghai Key Laboratory of Catalysis Technology for Polyolefins [LCTP-201301]

向作者/读者索取更多资源

N-beta-Hydroxyethyl pyrroles and indoles were constructed from the reaction of trans-4-hydoxyproline or indoline-2-carboxylic acid with electron deficient aldehydes via a domino [3+2] cycloaddition and ring-opening aromatization process under catalyst-free conditions. (C) 2015 Elsevier Ltd. All rights reserved.

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