期刊
TETRAHEDRON LETTERS
卷 56, 期 11, 页码 1328-1331出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.01.178
关键词
Frutilactones A and B; Diterpenoids; Rubiaceae
资金
- National Natural Science Foundation of China [21072230]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1193]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
A pair of 2,3-seco cafestol-type diterpenoid epimers, frutilactones A (1) and B (2) were isolated from twigs of Tricalysia fruticosa. Their structures were elucidated by comprehensively employing spectroscopic methods (MS and 1D/2D NMR) and ECD. Their inhibitory effects on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated, and a possible biogenetic pathway was also proposed. (C) 2015 Elsevier Ltd. All rights reserved.
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