期刊
TETRAHEDRON LETTERS
卷 56, 期 6, 页码 859-865出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.12.126
关键词
Pyrrole; Polystyrene supported p-toluenesulfonic acid; Heterogeneous catalyst; Solvent-free; Microwave
A solvent-free environmentally benign approach for the synthesis of diversified pyrrole derivatives has been described by the one-pot multicomponent reaction of aldehydes, nitroalkane, amine, and enolizable active C-H reactant using polystyrene supported p-toluenesulfonic acid (PS-PTSA) under microwave irradiation. In comparison to the conventional methods, this efficient green protocol provides remarkable advantages such as good to excellent yields, shorter reaction time, low cost, easy work-up procedure, and bypass for use of hazardous transition metal catalyst and organic solvent. (C) 2014 Elsevier Ltd. All rights reserved.
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