期刊
TETRAHEDRON LETTERS
卷 56, 期 30, 页码 4502-4504出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.05.114
关键词
Marine sponge; Agelas sp.; Bromopyrrole alkaloid; Agelamadin F; Tauroacidin E
资金
- Ministry of Education, Culture, Sports, Science and Technology of Japan
- Grants-in-Aid for Scientific Research [15K18885] Funding Source: KAKEN
A new structurally unique bromopyrrole alkaloid, agelamadin F (1), comprising oroidin and 3-hydroxypyridinium was isolated from an Okinawan marine sponge Agelas sp. together with tauroacidin E (2), a new bromopyrrole alkaloid possessing a taurine moiety. Six known bromopyrrole alkaloids, oroidin, tauroacidin A, sceptrin, ageliferin, nagelamide E, and agelongine were also isolated and identified. The structures of 1 and 2 were elucidated on the basis of spectroscopic evidences, while chiral HPLC analysis suggested tauroacidin E (2) to be a racemate. (C) 2015 Elsevier Ltd. All rights reserved.
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