期刊
TETRAHEDRON LETTERS
卷 56, 期 22, 页码 2917-2921出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.04.068
关键词
Pyrrolo[1,2-a]pyrimidine; Pyrido[1,2-a]pyrimidine; Aminopyrazole; Pyrazolo[3,4-b]pyridine; Cascade of two cyclization reaction
资金
- COLCIENCIAS
- Universidad del Valle
Novel fused pyrrolo[1,2-c]pyrimidines and pyrido[1,2-a]pyrimidine derivatives were prepared by a cascade of two cyclization reactions between pyrazolopyridinediamines 4 and omega-chloroketones 5-7 in ethanol as solvent and a catalytic amount of acetic acid. This approach provided the title compounds 8-10 in good yields and under mild simple one-step reaction conditions. The structures of the new compounds were unambiguously established by spectroscopic and analytical techniques. (C) 2015 Elsevier Ltd. All rights reserved.
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