期刊
TETRAHEDRON
卷 71, 期 38, 页码 6681-6688出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2015.07.051
关键词
Multicomponent reaction; Spirocycle; 1,3-Oxazine; Aldimine; Quinine; Electron-deficient alkyne
资金
- National Natural Science Foundation of China [21172189]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
A series of structurally diverse spirocyclic 1,3-oxazines were conveniently prepared from three-component reactions of alpha,beta-unsaturated N-arylaldimines, dialkyl acetylenedicarboxylate and quinones in dry acetonitrile without catalyst. Various quinones including p-benzoquinone, 1,4-naphthoquinone, acenaphthenequinone, and phenanthrenequinone as well as benzil were successfully used in the reaction to give the corresponding spirocyclic 1,3-oxazines in good yields. The diastereoisomers of the obtained spirocyclic 1,3-oxazines were elucidated by H-1 NMR spectra and single crystal structures. (C) 2015 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据