4.4 Article

Acid-catalyzed efficient Friedel Crafts reaction of indoles with N-Boc aminals

期刊

TETRAHEDRON
卷 71, 期 41, 页码 7869-7873

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2015.08.030

关键词

Aminals; Indoles; Lewis acids; Friedel-Crafts reaction

资金

  1. National Natural Science Foundation of China [21272068]
  2. Program for New Century Excellent Talents in University [NCET-13-0800]
  3. Fundamental Research Funds for the Central Universities

向作者/读者索取更多资源

An effective Friedel Crafts reaction between N-Boc aminals and N-Boc indoles catalyzed by copper(II) trifluoromethanesulfonate has been developed. The less accessible N-Boc imines could be generated in situ from N-Boc aminals. The reaction was achieved in moderate to good yields under mild conditions. (c) 2015 Elsevier Ltd. All rights reserved.

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