相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Jakob Loven et al.
CELL (2013)
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
Christopher J. Ott et al.
BLOOD (2012)
Bromodomain and Extra-terminal (BET) Bromodomain Inhibition Activate Transcription via Transient Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein
Koen Bartholomeeusen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Jake E. Delmore et al.
CELL (2011)
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Johannes Zuber et al.
NATURE (2011)
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Mark A. Dawson et al.
NATURE (2011)
Targeting MYC dependence in cancer by inhibiting BET bromodomains
Jennifer A. Mertz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Progress in the Discovery of Small-Molecule Inhibitors of Bromodomain-Histone Interactions
Chun-Wa Chung et al.
JOURNAL OF BIOMOLECULAR SCREENING (2011)
Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency
Xudong Li et al.
JOURNAL OF VIROLOGY (2010)
Suppression of inflammation by a synthetic histone mimic
Edwige Nicodeme et al.
NATURE (2010)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma
Kristopher A. Sarosiek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
Chi V. Dang et al.
CLINICAL CANCER RESEARCH (2009)
Stimulation of c-Myc transcriptional activity by vIRF-3 of Kaposi sarcoma-associated herpesvirus
Barbora Lubyova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs
Xiaocui Zhu et al.
BMC MOLECULAR BIOLOGY (2007)
K13 Blocks KSHV Lytic Replication and Deregulates vIL6 and hIL6 Expression: A Model of Lytic Replication Induced Clonal Selection in Viral Oncogenesis
Jinshun Zhao et al.
PLOS ONE (2007)
The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc
Jianyong Liu et al.
JOURNAL OF VIROLOGY (2007)
Deregulation of c-Myc in primary effusion lymphoma by Kaposi's sarcoma herpesvirus latency-associated nuclear antigen
D. Bubman et al.
ONCOGENE (2007)
The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation
Shwu-Yuan Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Human herpesvirus 8-encoded proteins with potential roles in virus-associated neoplasia
John Nicholas
FRONTIERS IN BIOSCIENCE-LANDMARK (2007)
Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest
Matthias Ottinger et al.
JOURNAL OF VIROLOGY (2006)
A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression
Kum-Joo Shin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes
Jianxin You et al.
JOURNAL OF VIROLOGY (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Human herpesvirus 8 (HHV-8)-associated peritoneal primary effusion lymphoma (PEL) in two HIV-negative elderly patients
E Boulanger et al.
AMERICAN JOURNAL OF HEMATOLOGY (2004)
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells
ZR Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Combined chemotherapy including high-dose methotrexate in KSHV/HHV8-associated primary effusion lymphoma
E Boulanger et al.
AMERICAN JOURNAL OF HEMATOLOGY (2003)
Genomic targets of the human c-Myc protein
PC Fernandez et al.
GENES & DEVELOPMENT (2003)
Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator
H Nakamura et al.
JOURNAL OF VIROLOGY (2003)
c-MYC: More than just a matter of life and death
S Pelengaris et al.
NATURE REVIEWS CANCER (2002)
Latency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication
AC Garber et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA
ME Ballestas et al.
JOURNAL OF VIROLOGY (2001)
Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma
YP Shou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)