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Gavin P. Dunn et al.
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Jia-Jean Yiin et al.
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Laura R. Pearce et al.
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Spatial Distribution of Protein Kinase A Activity during Cell Migration Is Mediated by A-kinase Anchoring Protein AKAP Lbc
Adriana A. Paulucci-Holthauzen et al.
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David Meiri et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
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Malignant gliomas in adults
Patrick Y. Wen et al.
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Stimulation of proliferation of U138-MG glioblastoma cells by gastrin-releasing peptide in combination with agents that enhance cAMP signaling
Caroline Brunetto de Farias et al.
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Protein kinase A-dependent phosphorylation modulates β1Pix guanine nucleotide exchange factor activity through 14-3-3β binding
Ahmed Chahdi et al.
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Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1α-mediated localization in living cells
Brent R. Martin et al.
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Nlichael J. Jarzynka et al.
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Jean-Francois Cote et al.
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Troy Payner et al.
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Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression
XM Cai et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme
C Giannini et al.
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GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
KL Rossman et al.
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Endothelin 1 induces β1Pix translocation and Cdc42 activation via protein kinase A-dependent pathway
A Chahdi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration
CM Grimsley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mediation of enhanced transcription of the IL-10 gene in T cells, upon contact with human glioma cells, by fas signaling through a protein kinase A-independent pathway
BC Yang et al.
JOURNAL OF IMMUNOLOGY (2003)
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
E Brugnera et al.
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Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells.
KL O'Connor et al.
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Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis
P Duchek et al.
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Localized Rac activation dynamics visualized in living cells
VS Kraynov et al.
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Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy
E Raymond et al.
DRUGS (2000)