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J. R. Molina et al.
ONCOGENE (2012)
Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression
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CANCER CELL (2011)
Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt
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EMBO REPORTS (2011)
mTOR-Dependent Regulation of PHLPP Expression Controls the Rapamycin Sensitivity in Cancer Cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Mislocalization of the E3 Ligase, β-Transducin Repeat-containing Protein 1 (β-TrCP1), in Glioblastoma Uncouples Negative Feedback between the Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase 1 (PHLPP1) and Akt
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The Deubiquitinating Enzyme USP-46 Negatively Regulates the Degradation of Glutamate Receptors to Control Their Abundance in the Ventral Nerve Cord of Caenorhabditis elegans
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JOURNAL OF NEUROSCIENCE (2011)
SCOP/PHLPP and its functional role in the brain
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MOLECULAR BIOSYSTEMS (2010)
Mst1 Is an Interacting Protein that Mediates PHLPPs' Induced Apoptosis
Meng Qiao et al.
MOLECULAR CELL (2010)
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
Martin Schwickart et al.
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FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination
Sirio Dupont et al.
CELL (2009)
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CELL (2009)
β-TrCP-Mediated Ubiquitination and Degradation of PHLPP1 Are Negatively Regulated by Akt
Xin Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Breaking the chains: structure and function of the deubiquitinases
David Komander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis
J. Liu et al.
ONCOGENE (2009)
The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
Wei-Lei Yang et al.
SCIENCE (2009)
PHUPPing the switch on Akt and protein kinase C signaling
John Brognard et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)
The phosphatase PHLPP controls the cellular levels of protein kinase C
Tianyan Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The ubiquitin-specific protease USP28 is required for MYC stability
Nikita Popov et al.
NATURE CELL BIOLOGY (2007)
PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms
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MOLECULAR CELL (2007)
PHLPP: A phosphatase that directly dephosphorylates akt, promotes apoptosis, and suppresses tumor growth
TY Gao et al.
MOLECULAR CELL (2005)
The many faces of β-TrCP E3 ubiquitin ligases:: reflections in the magic mirror of cancer
SY Fuchs et al.
ONCOGENE (2004)
Skp2 regulates Myc protein stability and activity
SY Kim et al.
MOLECULAR CELL (2003)