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Gemma Molyneux et al.
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Gina M. Bernardo et al.
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Preclinical mouse models for BRCA1-associated breast cancer
R. M. Drost et al.
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Xin-Hai Pei et al.
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Daisuke Yamaji et al.
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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
Elgene Lim et al.
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Mollie H. Wright et al.
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Suling Liu et al.
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Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia
Chanel E. Smart et al.
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Molecular basis for estrogen receptor α deficiency in BRCA1-linked breast cancer
Alison M. Hosey et al.
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Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues
Matthew R. Ramsey et al.
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p18Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers
Xin-Hai Pei et al.
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P18Ink4c, but not p27Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors
Feng Bai et al.
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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
Jason I. Herschkowitz et al.
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Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
Katherine E. Sleeman et al.
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The role of BRCA1 in transcriptional regulation and cell cycle control
P. B. Mullan et al.
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p18Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control
Feng Bai et al.
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EA Williamson et al.
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Generation of a functional mammary gland from a single stem cell
M Shackleton et al.
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A Ribeiro-Silva et al.
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The molecular pathology of hereditary breast cancer:: genetic testing and therapeutic implications
E Honrado et al.
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Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype
SR Lakhani et al.
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Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells
S Furuta et al.
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Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer
JB Arnes et al.
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Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues
XH Pei et al.
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Epithelial progenitors in the normal human mammary gland
J Stingl et al.
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The prognostic implication of the basal-like (cyclin Ehigh/p27low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer
WD Foulkes et al.
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BRCA1 functions as a breast stem cell regulator
WD Foulkes
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Binding and recognition in the assembly of an active BRCA1 /BARD1 ubiquitin-ligase complex
PS Brzovic et al.
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Haploinsufficiency of p18INK4c sensitizes mice to carcinogen-induced tumorigenesis
F Bai et al.
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Senescence aging, and malignant transformation mediated by p53 in mice lacking the Brcal full-length isoform
L Cao et al.
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Brca1 regulates in vitro differentiation of mammary epithelial cells
M Kubista et al.
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Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
XL Xu et al.
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The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
R Hashizume et al.
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CX Deng et al.
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