相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Requirement of ATM for Rapid p53 Phosphorylation at Ser46 without Ser/Thr-Gln Sequences
Masami Kodama et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization
H. Christian Reinhardt et al.
MOLECULAR CELL (2010)
Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents
S. Zenvirt et al.
ONCOGENE (2010)
Cdk2 Is Required for p53-Independent G2/M Checkpoint Control
Jon H. Chung et al.
PLOS GENETICS (2010)
Prospects for the Use of ATR Inhibitors to Treat Cancer
Jill M. Wagner et al.
PHARMACEUTICALS (2010)
Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
H. Christian Reinhardt et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
The combined status of ATM and p53 link tumor development with therapeutic response
Hai Jiang et al.
GENES & DEVELOPMENT (2009)
Cisplatin-Induced DNA Damage Activates Replication Checkpoint Signaling Components that Differentially Affect Tumor Cell Survival
Jill M. Wagner et al.
MOLECULAR PHARMACOLOGY (2009)
Axin determines cell fate by controlling the p53 activation threshold after DNA damage
Qinxi Li et al.
NATURE CELL BIOLOGY (2009)
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Yaroslava Ruzankina et al.
NATURE GENETICS (2009)
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
Matilde Murga et al.
NATURE GENETICS (2009)
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53
Surojit Sur et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1
Alessandra Blasina et al.
MOLECULAR CANCER THERAPEUTICS (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
Deborah Wilsker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis
Navjotsingh Pabla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
Human cancer cells require ATR for cell cycle progression following exposure to ionizing radiation
P. J. Hurley et al.
ONCOGENE (2007)
Targeting checkpoint kinase 1 in cancer therapeutics
Archie N. Tse et al.
CLINICAL CANCER RESEARCH (2007)
Loss of ataxia telangiectasia mutated- and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival
Deborah Wilsker et al.
MOLECULAR CANCER THERAPEUTICS (2007)
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage
Naoe Taira et al.
MOLECULAR CELL (2007)
ATM and ATR - Components of an integrated circuit
Paula J. Hurley et al.
CELL CYCLE (2007)
p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage
H. Christian Reinhardt et al.
CANCER CELL (2007)
Genetic knockouts and knockins in human somatic cells
Carlo Rago et al.
NATURE PROTOCOLS (2007)
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
Dong Zhang et al.
CELL (2006)
Chk1-dependent slowing of S-phase progression protects DT40 B-lymphoma cells against killing by the nucleoside analogue 5-fluorouracil
H. M. R. Robinson et al.
ONCOGENE (2006)
The ATM-mediated DNA-damage response: taking shape
Yosef Shiloh
TRENDS IN BIOCHEMICAL SCIENCES (2006)
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
A Jazayeri et al.
NATURE CELL BIOLOGY (2006)
Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells
L Jirmanova et al.
CELL CYCLE (2005)
Chk1 is essential for tumor cell viability following activation of the replication checkpoint
SH Cho et al.
CELL CYCLE (2005)
Improved methods for the generation of human gene knockout and knockin cell lines
O Topaloglu et al.
NUCLEIC ACIDS RESEARCH (2005)
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway
GK Alderton et al.
HUMAN MOLECULAR GENETICS (2004)
Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation
YN Rui et al.
EMBO JOURNAL (2004)
The role of p53 in chemosensitivity and radiosensitivity
WS El-Deiry
ONCOGENE (2003)
The Chk2 tumor suppressor is not required for p53 responses in human cancer cells
PV Jallepalli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
M O'Driscoll et al.
NATURE GENETICS (2003)
Checking on the fork: the DNA-replication stress-response pathway
AJ Osborn et al.
TRENDS IN CELL BIOLOGY (2002)
Live or let die: The cell's response to p53
KH Vousden et al.
NATURE REVIEWS CANCER (2002)
p53AlP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
K Oda et al.
CELL (2000)
Does p53 status influence tumor response to anticancer therapies?
KF Pirollo et al.
ANTI-CANCER DRUGS (2000)
分享论文
