相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers
Yoshifumi Baba et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Low expression of Mel-18 predicts poor prognosis in patients with breast cancer
B. -H. Guo et al.
ANNALS OF ONCOLOGY (2010)
Mel-18, a mammalian Polycomb gene, regulates angiogenic gene expression of endothelial cells
Ji-Hye Jung et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability
Sasidhar Vemula et al.
BLOOD (2010)
PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and -independent mechanisms in HepG2 cells
Tao Tian et al.
CARCINOGENESIS (2010)
Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer
William M. Merritt et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex
T. Qian et al.
ONCOGENE (2010)
Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1α
Yoon-Mi Lee et al.
CARCINOGENESIS (2009)
X-linked Inhibitor of Apoptosis Protein (XIAP) Regulates PTEN Ubiquitination, Content, and Compartmentalization
Celine Van Themsche et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
HIF at a glance
M. Christiane Brahimi-Horn et al.
JOURNAL OF CELL SCIENCE (2009)
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
Hui Xiong et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
PTEN regulate angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells
Jiachi Ma et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
Mel-18 negatively regulates INK4a/ARF-independent cell cycle progression via Akt inactivation in breast cancer
Jeong-Yeon Lee et al.
CANCER RESEARCH (2008)
PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a)
Brooke M. Emerling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
HIF-1 regulation: not so easy come, easy go
Mei Yee Koh et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF
Andreas-Claudius Hoffmann et al.
NEOPLASIA (2008)
SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1α ubiquitination and degradation
M. Tan et al.
ONCOGENE (2008)
PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis
Jing Fang et al.
CELLULAR SIGNALLING (2007)
Overexpression of PTEN induces cell growth arrest and apoptosis in human breast cancer ZR-75-1 cells
Xiangyong Li et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2007)
Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells
Wei-Jian Guo et al.
CANCER RESEARCH (2007)
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1α and mediates its destabilization in a VHL-independent manner
Daniela Fluegel et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Inhibitor of DNA binding 1 activates vascular endothelial growth factor through enhancing the stability and activity of hypoxia-inducible factor-1α
Hyun-Jun Kim et al.
MOLECULAR CANCER RESEARCH (2007)
Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins
Wei-Jian Guo et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Ubiquitination regulates PTEN nuclear import and tumor suppression
Lloyd C. Trotman et al.
CELL (2007)
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
Xinjiang Wang et al.
CELL (2007)
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3β
AM Al-Khouri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
DJ-1, a novel regulator of the tumor suppressor PTEN
RH Kim et al.
CANCER CELL (2005)
Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1α expression
JI Bárdos et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Stem colls and cancer: The polycomb connection
ME Valk-Lingbeek et al.
CELL (2004)
Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1α
YG Yoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1α, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling
HD Skinner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
CW Pugh et al.
SEMINARS IN CANCER BIOLOGY (2003)
Phosphorylation of HDM2 by Akt
M Ashcroft et al.
ONCOGENE (2002)
Activation of the HIF pathway in cancer
PH Maxwell et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2001)
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus - Implications for PTEN stability to proteasome-mediated degradation
J Torres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
ME Cockman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Mechanism of regulation of the hypoxia-inducible factor-lα by the von Hippel-Lindau tumor suppressor protein
K Tanimoto et al.
EMBO JOURNAL (2000)
分享论文
