相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Gambogic acid triggers DNA damage signaling that induces p53/p21Waf1/CIP1 activation through the ATR-Chk1 pathway
Jing-Jing Rong et al.
CANCER LETTERS (2010)
Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein
M. R. Abedini et al.
ONCOGENE (2010)
Phosphorylation and Degradation of MdmX Is Inhibited by Wip1 Phosphatase in the DNA Damage Response
Xinna Zhang et al.
CANCER RESEARCH (2009)
Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways
Gaoliang Ouyang et al.
CELL BIOLOGY INTERNATIONAL (2009)
PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas
David S. P. Tan et al.
CLINICAL CANCER RESEARCH (2009)
Recombinant adeno-associated virus encoding Epstein-Barr virus latent membrane proteins fused with heat shock protein as a potential vaccine for nasopharyngeal carcinoma
Jianqing Pan et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Cisplatin-Induced DNA Damage Activates Replication Checkpoint Signaling Components that Differentially Affect Tumor Cell Survival
Jill M. Wagner et al.
MOLECULAR PHARMACOLOGY (2009)
WIP1 phosphatase is a negative regulator of NF-κB signalling
Joanne Chew et al.
NATURE CELL BIOLOGY (2009)
Regulation of apoptosis-inducing factor-mediated, cisplatin-induced apoptosis by Akt
X. Yang et al.
BRITISH JOURNAL OF CANCER (2008)
The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways
Xiongbin Lu et al.
CANCER AND METASTASIS REVIEWS (2008)
Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells
Mohammad R. Abedini et al.
CANCER RESEARCH (2008)
DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G(2) arrest can occur independently of Chk1, Chk2 or MAPKAPK2
Wen-Hui Zhang et al.
CELL CYCLE (2008)
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
Deborah Wilsker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Characterization of the active site and a unique uncompetitive inhibitor of the PPM1-type protein phosphatase PPM1D
Yoshiro Chuman et al.
PROTEIN AND PEPTIDE LETTERS (2008)
Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function
Michael Fraser et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
The wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases
Hiroshi Yamaguchi et al.
BIOCHEMISTRY (2007)
The Wip1 phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop
Xiongbin Lu et al.
CANCER CELL (2007)
Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling
Jaana Jurvansuu et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage
H. Christian Reinhardt et al.
CANCER CELL (2007)
Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics
Zehan Chen et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Akt-mediated cisplatin resistance in ovarian cancer: Modulation of p53 action on caspase-dependent mitocliondrial death pathway
XK Yang et al.
CANCER RESEARCH (2006)
The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours
J Rauta et al.
BREAST CANCER RESEARCH AND TREATMENT (2006)
SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins
A Traven et al.
BIOESSAYS (2005)
P53C-terminal phosphorylation by CHM and CHK2 participates in the regulation of DNA-Damage-induced C-terminal acetylation
YH Ou et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer
TJ Shaw et al.
MOLECULAR THERAPY (2004)
Homeostatic regulation of base excision repair by a p53-induced phosphatase - Linking stress response pathways with DNA repair proteins
XB Lu et al.
CELL CYCLE (2004)
Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells
P Perego et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345
KC Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest
H Capasso et al.
JOURNAL OF CELL SCIENCE (2002)
Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines
LC Playle et al.
BRITISH JOURNAL OF CANCER (2002)
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
DV Bulavin et al.
NATURE GENETICS (2002)
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
H Zhao et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Cisplatinum and taxol induce different patterns of p53 phosphorylation
G Damia et al.
NEOPLASIA (2001)
The structure and expression of the murine wildtype p53-induced phosphatase 1 (Wip1) gene
J Choi et al.
GENOMICS (2000)
The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01
PR Graves et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)