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Megan S. Lim et al.
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Anne Fernandez-Vidal et al.
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Tiebang Kang et al.
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Pathobiology of ALK+ anaplastic large-cell lymphoma
Hesham M. Amin et al.
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Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf
M. Marzec et al.
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Yuxing Zhao et al.
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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
U Maurer et al.
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Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
J Rush et al.
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The glamour and gloom of glycogen synthase kinase-3
RS Jope et al.
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H Ruchatz et al.
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GSK-3-selective inhibitors derived from Tyrian purple indirubins
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Wnt signaling controls the phosphorylation status of β-catenin
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Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
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