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Ignacio Varela et al.
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M. Koslowski et al.
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Kyung Ju Lee et al.
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Andrew M. Roberts et al.
CANCER RESEARCH (2009)
Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
Gregory Bellot et al.
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Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
Patrick J. Pollard et al.
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John D. Gordan et al.
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The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF
Sophie Beyer et al.
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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
William G. Kaelin
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Hypoxia-inducible factor-1α inhibits self-renewal of mouse embryonic stem cells in vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway
Chul-Ho Jeong et al.
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Genome regulation by polycomb and trithorax proteins
Bernd Schuettengruber et al.
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Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein
Miguel A. Esteban et al.
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Regulation of E-cadherin expression by VHL and hypoxia-inducible factor
MA Esteban et al.
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The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-α
F Dayan et al.
CANCER RESEARCH (2006)
Epigenetic therapy of cancer: past, present and future
CB Yoo et al.
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Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene
N Pescador et al.
BIOCHEMICAL JOURNAL (2005)
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
RR Raval et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
HIF-1α induces cell cycle arrest by functionally counteracting Myc
M Koshiji et al.
EMBO JOURNAL (2004)
Oxygen sensing by HIF hydroxylases
CJ Schofield et al.
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BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
S Kothari et al.
ONCOGENE (2003)
Regulation of angiogenesis by hypoxia: role of the HIF system
CW Pugh et al.
NATURE MEDICINE (2003)
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
A Hergovich et al.
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Molecular basis of the VHL hereditary cancer syndrome
WG Kaelin
NATURE REVIEWS CANCER (2002)
The BCL2 family: Regulators of the cellular life-or-death switch
S Cory et al.
NATURE REVIEWS CANCER (2002)
HIF activation identifies early lesions in VHL kidneys: Evidence for site-specific tumor suppressor function in the nephron
SJ Mandriota et al.
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HIF-1, O2, and the 3 PHDs:: How animal cells signal hypoxia to the nucleus
GL Semenza
CELL (2001)
Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor α expression during hypoxia
S Narravula et al.
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Hypoxia induces the expression of the pro-apoptotic gene BNIP3
K Guo et al.
CELL DEATH AND DIFFERENTIATION (2001)
Evidence for the involvement of diacylglycerol. kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension
J Aragonés et al.
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