相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Julien H. Dey et al.
CANCER RESEARCH (2010)
Genetic Screen Identifies Insulin-like Growth Factor Binding Protein 5 as a Modulator of Tamoxifen Resistance in Breast Cancer
Bo Young Ahn et al.
CANCER RESEARCH (2010)
FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer
Nicholas Turner et al.
CANCER RESEARCH (2010)
Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways
Sandra E. Ghayad et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
N. Turner et al.
ONCOGENE (2010)
MYC regulation of a poor-prognosis metastatic cancer cell state
Anita Wolfer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Tamoxifen Induces Expression of Immune Response-Related Genes in Cultured Normal Human Mammary Epithelial Cells
Laura J. Schild-Hay et al.
CANCER RESEARCH (2009)
Estrogen receptor alpha gene ESR1 amplification may predict endocrine therapy responsiveness in breast cancer patients
Saori Tomita et al.
CANCER SCIENCE (2009)
The Role of Fibroblast Growth Factors in Tumor Growth
M. Korc et al.
CURRENT CANCER DRUG TARGETS (2009)
Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1
Mai Kanai et al.
GENE (2009)
Lapatinib Combined With Letrozole Versus Letrozole and Placebo As First-Line Therapy for Postmenopausal Hormone Receptor-Positive Metastatic Breast Cancer
Stephen Johnston et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared With Placebo Plus Letrozole in Patients With Estrogen Receptor-Positive Breast Cancer
Jose Baselga et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells
A. J. Sadler et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2009)
Biological Convergence of Cancer Signatures
Xavier Sole et al.
PLOS ONE (2009)
Correlating measurements across samples improves accuracy of large-scale expression profile experiments
Mariano Javier Alvarez et al.
GENOME BIOLOGY (2009)
Sparse representation and Bayesian detection of genome copy number alterations from microarray data
Roger Pique-Regi et al.
BIOINFORMATICS (2008)
Pathway analysis reveals functional convergence of gene expression profiles in breast cancer
Ronglai Shen et al.
BMC MEDICAL GENOMICS (2008)
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer
Elizabeth Iorns et al.
CANCER CELL (2008)
Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor
Selma Masri et al.
CANCER RESEARCH (2008)
GATA-3 and the regulation of the mammary luminal cell fate
Hosein Kouros-Mehr et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells
Joan S. Lewis-Wambi et al.
EUROPEAN JOURNAL OF CANCER (2008)
Absence of ESR1 amplification in a series of breast cancers
Jose Adelaide et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Double-blind, Randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: Results from EFECT
Stephen Chia et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
ESR1 gene amplification in breast cancer:: a common phenomenon?
Anne Vincent-Salomon et al.
NATURE GENETICS (2008)
ESR1 gene amplification in breast cancer:: a common phenomenon?
Lindsay A. Brown et al.
NATURE GENETICS (2008)
ESR1 gene amplification in breast cancer:: a common phenomenon?
Hugo M. Horlings et al.
NATURE GENETICS (2008)
Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer
Kerstin B. Meyer et al.
PLOS BIOLOGY (2008)
JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update
Jan Christian Bryne et al.
NUCLEIC ACIDS RESEARCH (2008)
Acomprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members
Xiaoqin Xu et al.
GENOME RESEARCH (2007)
Changes in breast cancer transcriptional profiles after treatment with the aromatase inhibitor, letrozole
William R. Miller et al.
PHARMACOGENETICS AND GENOMICS (2007)
Pathway analysis of gene signatures predicting metastasis of node-negative primary breast cancer
Jack X. Yu et al.
BMC CANCER (2007)
Integrated analysis of independent gene expression microarray datasets improves the predictability of breast cancer outcome
Zhe Zhang et al.
BMC GENOMICS (2007)
Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling
M. Beeram et al.
ANNALS OF ONCOLOGY (2007)
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
David J. Hunter et al.
NATURE GENETICS (2007)
Positive cross-regulatory loop ties GATA-3 to estrogen receptor α expression in breast cancer
Jerome Eeckhoute et al.
CANCER RESEARCH (2007)
Genome-wide association study identifies novel breast cancer susceptibility loci
Douglas F. Easton et al.
NATURE (2007)
Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer
Frederik Holst et al.
NATURE GENETICS (2007)
Zfx controls the self-renewal of embryonic and hematopoietic stem cells
Jose M. Galan-Caridad et al.
CELL (2007)
Unraveling the mechanisms of endocrine resistance in breast cancer: New therapeutic opportunities
Suleiman Massarweh et al.
CLINICAL CANCER RESEARCH (2007)
Statistical significance of cis-regulatory modules
Dustin E. Schones et al.
BMC BIOINFORMATICS (2007)
Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome
Vincent Vuaroqueaux et al.
BREAST CANCER RESEARCH (2007)
Role of receptor complexes in the extranuclear actions of estrogen receptor α in breast cancer
Robert X-D Song et al.
ENDOCRINE-RELATED CANCER (2006)
Resistance to endocrine therapy in breast cancer: exploiting estrogen receptor/growth factor signaling crosstalk
Suleiman Massarweh et al.
ENDOCRINE-RELATED CANCER (2006)
GATHER: a systems approach to interpreting genomic signatures
Jeffrey T. Chang et al.
BIOINFORMATICS (2006)
Genome-wide analysis of estrogen receptor binding sites
Jason S. Carroll et al.
NATURE GENETICS (2006)
Estrogen-independent proliferation is present in estrogen-receptor HER2-positive primary breast cancer after neoadjuvant letrozole
Matthew J. Ellis et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Changes in oestrogen receptor-α and -β during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells
L. E. Shaw et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2006)
Genetic regulators of large-scale transcriptional signatures in cancer
AS Adler et al.
NATURE GENETICS (2006)
ASD: a bioinformatics resource on alternative splicing
Stefan Stamm et al.
NUCLEIC ACIDS RESEARCH (2006)
TRANSFAC (R) and its module TRANSCompel (R): transcriptional gene regulation in eukaryotes
V. Matys et al.
NUCLEIC ACIDS RESEARCH (2006)
Farnesylthiosalicylic acid blocks mammalian target of rapamycin signaling in breast cancer cells
W Yue et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer
N Normanno et al.
ENDOCRINE-RELATED CANCER (2005)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells
E Balciunaite et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Long-term estradiol deprivation in breast cancer cells up-regulates growth factor signaling and enhances estrogen sensitivity
RJ Santen et al.
ENDOCRINE-RELATED CANCER (2005)
Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation
LA Martin et al.
ENDOCRINE-RELATED CANCER (2005)
Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole
D Jelovac et al.
CANCER RESEARCH (2005)
The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation
GJ Sabnis et al.
CANCER RESEARCH (2005)
Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance
SRD Johnston et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
Mechanisms of resistance to aromatase inhibitors
M Dowsett et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance
M Dowsett et al.
BREAST CANCER RESEARCH AND TREATMENT (2005)
affy -: analysis of Affymetrix GeneChip data at the probe level
L Gautier et al.
BIOINFORMATICS (2004)
Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells
ML Bowie et al.
ONCOGENE (2004)
Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (Faslodex, Fulvestrant)
KB Bouker et al.
CANCER RESEARCH (2004)
Tamoxifen resistance by a conformational arrest of the estrogen receptor α after PKA activation in breast cancer
R Michalides et al.
CANCER CELL (2004)
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
XJ Ma et al.
CANCER CELL (2004)
Bioconductor: open software development for computational biology and bioinformatics
RC Gentleman et al.
GENOME BIOLOGY (2004)
Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling
R Clarke et al.
ONCOGENE (2003)
Adaptive hypersensitivity following long-term estrogen deprivation: involvement of multiple signal pathways
W Yue et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2003)
Regulation of FGF receptor-2 expression by transcription factor E2F-1
E Tashiro et al.
ONCOGENE (2003)
Enhanced estrogen receptor (ER) α, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation
LA Martin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells
JM Knowlden et al.
ENDOCRINOLOGY (2003)
An open randomised trial of second-line endocrine therapy in advanced breast cancer: comparison of the aromatase inhibitors letrozole and anastrozole
C Rose et al.
EUROPEAN JOURNAL OF CANCER (2003)
Estrogen receptor phosphorylation
DA Lannigan
STEROIDS (2003)
A gene-expression signature as a predictor of survival in breast cancer.
MJ van de Vijver et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation
CMW Chan et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2002)
American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for women with hormone receptor-positive breast cancer: Status report 2002
EP Winer et al.
JOURNAL OF CLINICAL ONCOLOGY (2002)
American Society of Clinical Oncology technology assessment of pharmacologic interventions for breast cancer risk reduction including tamoxifen, raloxifene, and aromatase inhibition
RT Chlebowski et al.
JOURNAL OF CLINICAL ONCOLOGY (2002)
Adaptive hypersensitivity to estradiol: potential mechanism for secondary hormonal responses in breast cancer patients
R Santen et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2001)
Insulin-like growth factor receptor levels are regulated by cell density and by long term estrogen deprivation in MCF7 human breast cancer cells
RL Stephen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex)
RA McClelland et al.
ENDOCRINOLOGY (2001)
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α -: A new model for anti-estrogen resistance
RA Campbell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Loss of growth inhibitory effects of retinoic acid in human breast cancer cells following long-term exposure to retinoic acid
R Stephen et al.
BRITISH JOURNAL OF CANCER (2000)
Estradiol hypersensitivity and mitogen-activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo
WS Shim et al.
ENDOCRINOLOGY (2000)
分享论文
