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X. Wang et al.
TUMOR BIOLOGY (2009)
Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabilization of β-catenin-TCF interaction
Xiao-qing Gan et al.
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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
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Wwox hypomorphic mice display a higher incidence of B-Cell lymphomas and develop testicular atrophy
John H. Ludes-Meyers et al.
GENES CHROMOSOMES & CANCER (2007)
Association of Wwox with ErbB4 in breast cancer
Rami I. Aqeilian et al.
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Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling
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Inactivation of the WWOX gene accelerates forestomach tumor progression in vivo
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Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
Josipa Bilic et al.
SCIENCE (2007)
Targeted deletion of Wwox reveals a tumor suppressor function
Rami I. Aqeilan et al.
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Inhibition of breast cancer cell growth in vitro and in vivo: Effect of restoration of Wwox expression
Dimitrios Iliopoulos et al.
CLINICAL CANCER RESEARCH (2007)
Physical association with WWOX suppresses c-Jun transcriptional activity
Eugenio Gaudio et al.
CANCER RESEARCH (2006)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
Site-specific casein kinase 1ε-dependent phosphorylation of Dishevelled modulates β-catenin signaling
Laura K. Klimowski et al.
FEBS JOURNAL (2006)
WWOX -: the FRA16D cancer gene:: Expression correlation with breast cancer progression and prognosis
E Pluciennik et al.
EJSO (2006)
Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas
FJ Pimenta et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
A Kikuchi et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2006)
Wnt signaling: is the party in the nucleus?
Karl Willert et al.
GENES & DEVELOPMENT (2006)
Casein kinase 1γ couples Wnt receptor activation to cytoplasmic signal transduction
G Davidson et al.
NATURE (2005)
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
X Zeng et al.
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WWOX gene restoration prevents lung cancer growth in vitro and in vivo (Publication with Expression of Concern. See vol. 114, 2017)
M Fabbri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Concordant loss of fragile gene expression early in breast cancer development
G Guler et al.
PATHOLOGY INTERNATIONAL (2005)
WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function
RI Aqeilan et al.
CANCER RESEARCH (2005)
AIP4 restricts transforming growth factor-β signaling through a ubiquitination-independent mechanism
F Lallemand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer
D Iliopoulos et al.
ONCOGENE (2005)
17β-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro:: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo
NS Chang et al.
ONCOGENE (2005)
Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status
M Nunez et al.
BREAST CANCER RESEARCH AND TREATMENT (2005)
The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma -: Correlations with clinical features
G Guler et al.
CANCER (2004)
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis
T Kuroki et al.
CLINICAL CANCER RESEARCH (2004)
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog
RI Aqeilan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Casein kinase Iε modulates the signaling specificities of dishevelled
F Cong et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2γ transcription factor
RI Aqeilan et al.
CANCER RESEARCH (2004)
WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins
JH Ludes-Meyers et al.
ONCOGENE (2004)
Wnt proteins induce dishevelled phosphorylation via an LRP5/6-Independent mechanism, irrespective of their ability to stabilize β-catenin
JM González-Sancho et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Casein kinase Iε enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of β-catenin
S Hino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Runnin' with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
KA Wharton
DEVELOPMENTAL BIOLOGY (2003)
WWOX, the common chromosomal fragile site, FRA16D, cancer gene
JH Ludes-Meyers et al.
CYTOGENETIC AND GENOME RESEARCH (2003)
Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors
K Driouch et al.
ONCOGENE (2002)
Wnt signaling in breast cancer: have we come full circle?
AMC Brown
BREAST CANCER RESEARCH (2001)
WWOX:: A candidate tumor suppressor gene involved in multiple tumor types
AJW Paige et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iε
M Kishida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
NS Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The protein-protein interaction map of Helicobacter pylori
JC Rain et al.
NATURE (2001)
Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein
SI Hino et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Inhibition of Wnt signaling pathway by a novel axin-binding protein
T Kadoya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Common chromosomal fragile site FRA16D sequence:: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells
K Ried et al.
HUMAN MOLECULAR GENETICS (2000)
Colocalization and redistribution of dishevelled and actin during Wnt-induced mesenchymal morphogenesis
MA Torres et al.
JOURNAL OF CELL BIOLOGY (2000)
β-catenin, a novel prognostic marker for breast cancer:: Its roles in cyclin D1 expression and cancer progression
SY Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)