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JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
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T Kuwana et al.
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L Chen et al.
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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
JE Chipuk et al.
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The first α helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins bid and PUMA
PF Cartron et al.
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JA Yethon et al.
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A Cuconati et al.
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Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway
B Gillissen et al.
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M Marani et al.
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WX Zong et al.
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A Nechushtan et al.
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A Scorilas et al.
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Structure of Bax: Coregulation of dimer formation and intracellular localization
M Suzuki et al.
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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
R Eskes et al.
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