期刊
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
卷 70, 期 5, 页码 325-331出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/oemed-2012-100963
关键词
-
资金
- Albacete: Fondo de Investigaciones Santarias (FIS) [97/0035-01, 99/0034-01, 99/0034-02]
- Hospital Universitario de Albacete
- Consejeria de Sanidad
- Antwerp: FWO (Fund for Scientific Research)-Flanders Belgium [G.0402.00]
- University of Antwerp
- Flemish Health Ministry
- Barcelona: SEPAR, Public Health Service [R01 HL62633-01]
- Fondo de Investigaciones Santarias (FIS) [97/0035-01, 99/0034-01, 99/0034-02]
- CIRIT [1999SGR 00241]
- 'Instituto de Salud Carlos III' Red de Centros RCESP [C03/09, C03/011]
- Red RESPIRA [C03/011]
- Basel: Swiss National Science Foundation
- Swiss Federal Office for Education and Science
- Swiss National Accident Insurance Fund (SUVA)
- Bergen: Norwegian Research Council
- Norwegian Asthma and Allergy Association (NAAF)
- Glaxo Wellcome AS
- Norway Research Fund
- Bordeaux: Institut Pneumologique d'Aquitaine
- Erfurt: GSF-National Research Centre for Environment and Health
- Deutsche Forschungsgemeinschaft (DFG) [FR 1526/1-1, MA 711/4-1]
- Galdakao: Basque Health Dept.
- Goteborg: Swedish Heart Lung Foundation
- Swedish Foundation for Health Care Sciences and Allergy Research
- Swedish Asthma and Allergy Foundation
- Swedish Cancer and Allergy Foundation
- Grenoble: Programme Hospitalier de Recherche Clinique-DRC de Grenoble [2610]
- Ministry of Health
- Direction de la Recherche Clinique
- Ministere de l'Emploi et de la Solidarite
- Direction Generale de la Sante
- CHU de Grenoble
- Comite des Maladies Respiratoires de l'Isere
- Hamburg: GSF-National Research Centre for Environment and Health
- Ipswich and Norwich: Asthma UK
- National Asthma Campaign (UK)
- Huelva: Fondo de Investigaciones Santarias (FIS) [97/0035-01, 99/0034-01, 99/0034-02]
- Montpellier: Programme Hospitalier de Recherche Clinique-DRC de Grenoble [2610]
- Direction Regionale des Affaires Sanitaires et Sociales Languedoc-Roussillon
- Oviedo: Fondo de Investigaciones Santarias (FIS) [97/0035-01, 99/0034-01, 99/0034-02]
- Paris: Ministere de l'Emploi et de la Solidarite
- UCB-Pharma (France)
- Aventis (France)
- Glaxo France
- Programme Hospitalier de Recherche Clinique-DRC de Grenoble [2610]
- Pavia: Glaxo-SmithKline Italy
- Italian Ministry of University and Scientific and Technological Research (MURST)
- Local University (Pavia, Italy)
- Portland: American Lung Association of Oregon
- Northwest Health Foundation
- Collins Foundation
- Merck Pharmaceutical
- Reykjavik: Icelandic Research Council
- Icelandic University Hospital Fund
- Tartu: Estonian Science Foundation
- Turin: ASL 4 Regione Piemonte (Italy)
- AO CTO/ICORMA Regione Piemonte (Italy)
- Ministero dell'Universita e della Ricerca Scientifica (Italy)
- Glaxo Wellcome spa (Verona, Italy)
- Umea: Swedish Heart Lung Foundation
- Uppsala: Swedish Heart Lung Foundation
- Verona: University of Verona
- Glaxo-Smith Kline Italy
- Medical Research Council [G0901214, G0801056B] Funding Source: researchfish
- MRC [G0901214] Funding Source: UKRI
Objectives To study new onset of adult asthma in relation to dampness and moulds in dwelling places. Methods Totally, 7104 young adults from 13 countries who participated in the European Community Respiratory Health Survey (ECRHS I and II) who did not report respiratory symptoms or asthma at baseline were followed prospectively for 9 years. Asthma was assessed by questionnaire data on asthmatic symptoms and a positive metacholine challenge test at follow-up. Data on the current dwelling was collected at the beginning and at the end of the follow-up period by means of an interviewer-led questionnaire, and by inspection. Relative risks (RR) for new onset asthma were calculated with log-binomial models adjusted for age, sex, smoking and study centre. Results There was an excess of new asthma in subjects in homes with reports on water damage (RR 1.46; 95% CI 1.09 to 1.94) and indoor moulds (RR=1.30; 95% CI 1.00 to 1.68) at baseline. A dose-response effect was observed. The effect was stronger in those with multisensitisation and in those sensitised to moulds. Observed damp spots were related to new asthma (RR=1.49; 95% CI 1.00 to 2.22). The population-attributable risk was 3-10% for reported, and 3-14% for observed dampness/moulds. Conclusions Dampness and mould are common in dwellings, and contribute to asthma incidence in adults.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据