Foreign-Body Granuloma After Injection of Calcium Hydroxylapatite for Type III Stress Urinary Incontinence

BACKGROUND: Foreign-body granuloma is a potential complication of periurethral injection of calcium hydroxylapatite for the treatment of type Ill stress urinary incontinence. CASES: We present two cases of foreign-body granuloma formation after periurethral injection of calcium hydroxylapatite for type Ill stress urinary incontinence. Excision of the lesion resulted in cessation of pain in a symptomatic patient; however, it led to the resumption of stress urinary incontinence in both cases. CONCLUSION: Foreign-body granuloma is not the normative response to periurethral bulking with calcium hydroxylapatite. However, granuloma should be considered when a periurethral mass is encountered after injection of calcium hydroxylapatite for type Ill stress urinary incontinence. (Obstet Gynecol 2011;118:418-21) DOI: 10.1097/AOG.0b013e3182161953