4.4 Article

Long-Term Results of Gastric Bypass Surgery in Morbidly Obese Type 1 Diabetes Patients

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OBESITY SURGERY
卷 20, 期 4, 页码 506-508

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SPRINGER
DOI: 10.1007/s11695-010-0074-6

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Type 1 diabetes; Vascular complications; Prevention; Morbid obesity; Gastric bypass

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Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented. Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery. Their maximum body weight reduction noted during the follow-up was between 27% and 31% of baseline body weight, insulin requirement decreased from 0.6-0.95 to 0.3-0.83 IU/kg, and absolute reduction in HbA(1c) was 3-4%. Significant improvement in blood pressure, plasma lipid profile, and microalbuminuria was noted. RYGB surgery in morbidly obese type 1 diabetes patients leads to a significant and maintained weight loss and results in remarkable improvement in blood glucose control and concomitant disorders. Bariatric surgery should be recommended to significantly obese type 1 diabetes patients as a means of reduction of vascular complications risk.

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