期刊
OBESITY SURGERY
卷 20, 期 4, 页码 454-461出版社
SPRINGER
DOI: 10.1007/s11695-009-0033-2
关键词
Obesity; Menopause; Sleep apnea; Pulmonary function; Obesity hypoventilation
类别
资金
- Novo Nordisk Pharma [01/0066]
- CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM)
- CIBER Enfermedades Respiratorias (CIBERER)
There is a strong association between sleep-disordered breathing (SDB) and obesity. However, there are no studies addressed to determining the prevalence of SDB in morbidly obese premenopausal women, the most frequent group of patients requiring bariatric surgery. To evaluate the prevalence and characteristics of sleep apnea-hypopnea syndrome (SAHS) and obesity hypoventilation syndrome (OHS) in morbidly obese pre-menopausal women included in a program of bariatric surgery. A total of 88 consecutive morbidly obese pre-menopausal women (38.3 +/- 8.1 years, body mass index (BMI) 48.0 +/- 6.7 kg/m(2)) being evaluated for bariatric surgery at the outpatient obesity unit of a university hospital were prospectively recruited. SDB examinations included a non-attended respiratory polygraphy, pulmonary function testing, and an awake arterial gasometry. SAHS was defined as an apnea-hypopnea index (AHI) a parts per thousand yen10 events per hour and patients were divided in non-SAHS (AHI < 10), mild (AHI: 10-20), moderate (AHI: 21-30), and severe (AHI > 30). OHS was defined as the presence of hypercapnia (PaCO2 > 45). Somnolence was evaluated using the Epworth sleepiness scale. A total of 66 (75.0%) obese patients had SAHS: 25 (28.4%) mild, 14 (15.9%) moderate, and 27 (30.6%) severe. Seven (7.9%) obese patients presented OHS. Excessive daily somnolence was recorded in only 11 (16.6%) of the obese women with SAHS. In multiple regression analysis, BMI was the only variable independently associated with SAHS severity. Due to its high prevalence and severity, it should be recommended to investigate SDB in all morbidly obese pre-menopausal women awaiting bariatric surgery even in the absence of excessive daytime sleepiness.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据