期刊
OBESITY FACTS
卷 11, 期 4, 页码 344-353出版社
KARGER
DOI: 10.1159/000492116
关键词
Polyunsaturated fatty acids; Omegas; Obesity; Adiposity; Adiponectin
资金
- CONACyT [Salud-2013-01-202540]
Objective: The aim of this study was to analyze dietary omega-6:omega-3 polyunsaturated fatty acid (PUFA) ratio and its association with adiposity and serum adiponectin levels in a Mexican population. Methods: In this cross-sectional study, individuals with a BMI >= 18.5 kg/m(2), were classified using four methods to measure adiposity. Parameters of body composition were measured by InBody 3.0. Diet intake was evaluated prospectively using a 3-day written food record. Serum high-molecular weight adiponectin isoform was measured using an ELISA assay. Biochemical and adiposity variables were analyzed by tertiles of dietary omega-6:omega-3 PUFA ratio. Results: A total of 170 subjects were recruited with a mean age of 36.9 +/- 11.8 years. The 73.5% of subjects were women. Subjects in the higher tertile of dietary omega-6:omega-3 PUFA ratio had more adiposity and higher levels of triglycerides, VLDL-c, glucose, insulin and HOMA-IR than those in the first tertile (p < 0.05). Adiponectin levels showed a trend according to dietary omega-6:omega-3 PUFA ratio (p = 0.06). A linear regression model showed that waist circumference, insulin, and HOMA-IR have positive associations with dietary omega-6:omega-3 PUFA ratio. Conclusion: This study suggests that high dietary omega-6:omega-3 PUFA ratio is positively associated with excessive adiposity and worse metabolic profile. (c) 2018 The Author( s) Published by S. Karger GmbH, Freiburg
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