期刊
OBESITY
卷 23, 期 1, 页码 7-15出版社
WILEY
DOI: 10.1002/oby.20967
关键词
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资金
- NCI NIH HHS [R01 CA164166] Funding Source: Medline
- NIA NIH HHS [P30 AG028740] Funding Source: Medline
- NICHD NIH HHS [P50 HD073063] Funding Source: Medline
- NIDDK NIH HHS [P30 DK048520] Funding Source: Medline
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [P50HD073063] Funding Source: NIH RePORTER
- NATIONAL CANCER INSTITUTE [R01CA164166] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [ZIADK013036, P30DK048520] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [P30AG028740] Funding Source: NIH RePORTER
ObjectivesThe National Institutes of Health, led by the National Heart, Lung, and Blood Institute, organized a working group of experts to discuss the problem of weight regain after weight loss. A number of experts in integrative physiology and behavioral psychology were convened with the goal of merging their perspectives regarding the barriers to scientific progress and the development of novel ways to improve long-term outcomes in obesity therapeutics. The specific objectives of this working group were to: (1) identify the challenges that make maintaining a reduced weight so difficult; (2) review strategies that have been used to improve success in previous studies; and (3) recommend novel solutions that could be examined in future studies of long-term weight control. ResultsSpecific barriers to successful weight loss maintenance include poor adherence to behavioral regimens and physiological adaptations that promote weight regain. A better understanding of how these behavioral and physiological barriers are related, how they vary between individuals, and how they can be overcome will lead to the development of novel strategies with improved outcomes. ConclusionsGreater collaboration and cross-talk between physiological and behavioral researchers is needed to advance the science and develop better strategies for weight loss maintenance.
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