期刊
OBESITY
卷 19, 期 5, 页码 982-987出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/oby.2010.249
关键词
-
资金
- National Institutes of Diabetes, Digestive, and Kidney Disease [5R01DK054713-07, K24DK065018]
- National Center for Research Resources [UL1RR024134]
Little is known about binge eating (BE) in adolescents. The primary aim of the present study was to examine the relationship between BE and weight loss in adolescents (BMI >= 95th percentile) enrolled in a randomized controlled trial of behavioral and pharmacologic treatment of obesity. Participants were 82 treatment-seeking adolescents (BMI = 37.9 +/- 3.8 kg/m(2); age = 14.1 +/- 1.2 years; 67% females; 42% African American, 55% white). Participants completed the Children's Depression Inventory (CDI), the Piers Harris Self-Esteem Questionnaire, and the Eating Inventory (including cognitive restraint, disinhibition, and hunger scales). BE was assessed by a questionnaire and a confirmatory interview. At baseline, 24% of participants met criteria for BE (N = 13 met full BE disorder (BED) criteria; N = 7 met subthreshold BE). There were no significant differences in percentage reduction in initial BMI between participants with or without BE at month 6 (-7.0 +/- 1.6 vs. -6.9 +/- 0.9%) or month 12 (-8.8 +/- 2.4 vs. -8.3 +/- 1.3%) (omnibus main effect BE P = 0.89, interaction BE x time P = 0.84, interaction BE x drug P = 0.61). The rate of BE declined significantly over time from 24% (n = 20) at baseline to 8% (n = 6) at month 6 and 3% (n = 2) at month 12 (P = 0.003). There were significant decreases in hunger and disinhibition as well as an increase in cognitive restraint over time (all P = 0.0001). Findings suggest a combination of behavioral and pharmacologic therapy may produce both weight loss and improvement in BE.
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