期刊
NUTRITION REVIEWS
卷 69, 期 8, 页码 432-448出版社
OXFORD UNIV PRESS INC
DOI: 10.1111/j.1753-4887.2011.00400.x
关键词
daidzein; estrogen receptor beta; S-equol; soy isoflavones
Many clinical studies have been carried out to determine the health benefits of soy protein and the isoflavones contained in soy. S-equol is not present in soybeans but is produced naturally in the gut of certain individuals, particularly Asians, by the bacterial biotransformation of daidzein, a soy isoflavone. In those intervention studies in which plasma S-equol levels were determined, a concentration of >5-10 ng/mL has been associated with a positive outcome for vasomotor symptoms, osteoporosis (as measured by an increase in bone mineral density), prostate cancer, and the cardiovascular risk biomarkers low-density lipoprotein cholesterol and C-reactive protein. These studies suggest that S-equol may provide therapeutic benefits for a number of medical needs. (C) 2011 International Life Sciences Institute
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