期刊
NUTRITION REVIEWS
卷 68, 期 12, 页码 S112-S118出版社
OXFORD UNIV PRESS INC
DOI: 10.1111/j.1753-4887.2010.00346.x
关键词
brain; folate; homocysteine; one-carbon metabolism; vitamin B-12
资金
- US Department of Agriculture (USDA) [58-1950-7-707, 51520-008-04S]
Deficiencies of the vitamins folate, B-12, and B-6 are associated with neurological and psychological dysfunction and with congenital defects. In the elderly, cognitive impairment and incident dementia may be related to the high prevalence of inadequate B vitamin status and to elevations of plasma homocysteine. Plausible mechanisms include homocysteine neurotoxicity, vasotoxicity, and impaired S-adenosylmethionine-dependent methylation reactions vital to central nervous system function. In light of this, it is imperative to find safe ways of improving vitamin B status in the elderly without exposing some individuals to undue risk.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据