期刊
NUTRITION RESEARCH REVIEWS
卷 24, 期 1, 页码 111-117出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0954422411000011
关键词
Trans-fatty acids; Atherosclerosis; Cholesterol; LDL; CVD; Risk factors; Diabetes
资金
- ANR - Agence Nationale de la Recherche
- French National Research Agency
- National de Recherche en Alimentation et Nutrition Humaine [ANR-05-PNRA, 5.E.24]
The various positional isomers of oleic acid (18 : 1 Delta 9c or 9c-18 : 1) may have distinct biological effects. Detrimental effects of consumption of industrial trans-fatty acids (TFA) (elaidic acid; 18 : 1 Delta 9t) from partially hydrogenated vegetable oils on CVD risk factors are well documented. In addition, epidemiological data suggest that chronic consumption of industrial sources of TFA could alter insulin sensitivity and predispose for type 2 diabetes. However, intervention studies on this issue have remained inconclusive. Moreover, very little information is available on the effect of natural sources of TFA (vaccenic acid; 18 : 1 Delta 11t) coming from dairy products and ruminant meat on the development of CVD and type 2 diabetes. The review focuses on the impact of the consumption of ruminant TFA in relation to cardiovascular risk factors, inflammation and type 2 diabetes.
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