期刊
NUTRITION
卷 27, 期 10, 页码 1029-1033出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nut.2010.11.012
关键词
Iodine nutrition; Pregnancy; Epidemiology
资金
- Fundacion Sal y Salud, Barcelona
Objective: Catalonia (Spain) has a historically worse situation of mild iodine deficiency in the Pyrenees Mountains compared with the coastal region. The aim of this study was to evaluate the current iodine status in pregnant women living in these two areas. Methods: An epidemiologic prospective survey included 267 consecutive pregnancies in the Catalan mountains (n = 139) and coast (n = 128) studied during the first trimester: an additional subset of 135 women from the initial cohort was available for evaluation in the third trimester. Urinary iodine (UI) was measured, and questionnaires to determine iodized salt and sea fish consumption and potassium iodide supplementation were administered. Results: The median UI in the first trimester was 163 mu g/L for the entire cohort, with differences between mountain and coastal regions (209 versus 142 mu g/L, P = 0.007). The highest prevalence of iodized salt consumption was in the mountain area (58% versus 36.4%, P < 0.001). For the entire group, a higher median UI was found in iodized salt consumers compared with non-consumers (193 versus 134 mu g/L, P < 0.001). In the third trimester, an increase of median UI was seen in those to whom iodine supplements were given during pregnancy (190 versus 154 mu g/L, P = 0.015). Conclusion: A reversal in the historically iodine-deficient situation was observed in the Catalan Pyrenees compared with the coastal area, with a globally acceptable iodine status in pregnant women of the two geographic locations. Iodized salt consumption seems to have contributed to maintaining an acceptable iodine status in this population. (C) 2011 Elsevier Inc. All rights reserved.
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