期刊
NUTRITION
卷 25, 期 4, 页码 379-384出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nut.2008.09.012
关键词
Iron; Oxidative stress; Malondialdehyde; Protein carbonyls; Non-communicable chronic diseases
资金
- Fundacao de Apoio a Pesquisa do Distrito Federal
- Coordinacao de aperfeicoamento de pessoal de nivel superior (CAPES)
- Graduate Program in Human Nutrition
- University of Brasflia, Brazil
Objective: Although essential to many vital processes, iron catalyzes reactions that produce reactive oxygen species, which are associated with the increased risk of non-communicable chronic diseases and precocious aging. This study investigated whether ferritin, hemoglobin concentration, and dietary iron consumption are related to oxidative stress biomarkers in adults. Methods: Data were collected from 134 allegedly healthy subjects >18 y of age who were randomly selected to participate in a cross-sectional study as part of the pilot project Prevalence of Risk Factors for Non-communicable Chronic Diseases in the Federal District, Brazil (VIVA Saude-DF). Serum ferritin, malondialdehyde (MDA) and protein carbonyl concentrations, hemoglobin, and dietary iron consumption were analyzed. Results: A weak positive correlation (r = 0.189, P = 0.032) and association (P = 0.046) was observed for serum ferritin and MDA. Hemoglobin concentrations were positively associated with serum MDA (P = 0.040). Dietary iron intake and serum protein carbonyl concentrations showed a weak positive correlation (r = 0.173, P = 0.046) for all subjects. Iron intake by women was positively associated with serum protein carbonyl (P = 0.03). A lower serum MDA concentration was found in ferritin-deficient subjects (P = 0.015) and men with anemia (P = 0.011). Conclusion; These results suggest that low levels of iron may reduce oxidative stress. (C) 2009 Published by Elsevier Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据