期刊
SYNTHETIC COMMUNICATIONS
卷 45, 期 8, 页码 982-992出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2014.999340
关键词
Antimicrobial activity; 2-cyanoacetohydrazide; thienopyrimidines; triazolothienopyrimidines
2-Cyanoacetohydrazide and 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene derivatives were exploited as starting materials for the syntheses of novel thienopyrimidines and triazolothienopyrimidines. The proclivity of these compounds toward one-carbon donor reagents such as carbon disulfide, phenyl isothiocyanate, and aromatic aldehydes was investigated. The structures of all synthesized compounds were ascertained by spectral and analytical data. The antimicrobial activity of the target synthesized compounds was tested against various microorganisms.
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