4.3 Article

Straightforward Approach Toward Dihydrothiazoles via Intramolecular Bromocyclization

期刊

SYNTHETIC COMMUNICATIONS
卷 45, 期 18, 页码 2142-2147

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2015.1067707

关键词

Benzoyl chloride; bromocyclization; dihydrothiazole; N-bromosuccinimide (NBS)

资金

  1. Tehran University of Medical Sciences, International Campus

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An intramolecular bromonium ion-assisted cyclization with sulfur as an internal nucleophile is described. Starting from benzoyl chlorides, this method provides an easy procedure for the synthesis of dihydrothiazole derivatives in moderate to good yields.

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