Selective C-Si Bond Formation through C-H Functionalization

Silylation of hydrocarbons is one of the most important transformations due to the diverse application of organosilanes. Continuous progress is being made in organosilane synthesis particularly through direct C-H activation/functionalization. This minireview compiles various processes reported for C-Si bond formation from 2000-2014, through C-H activation/functionalization (proximal and remote) and metal-free approaches. 1 Introduction 2 C-Si Bond Formation through C-H Activation in Intermolecular Fashion 2.1 C-Si Bond Formation through Direct C(sp(2))-H Activation 2.2 C-Si Bond Formation through Directing Group Assisted C(sp(2))-H Activation 2.3 C-Si Bond Formation through sp(3) C-H Activation 3 C-Si Bond Formation through Proximal C-H Activation/Functionalization in Intramolecular Fashion 3.1 Intramolecular C-Si Bond Formation through C(sp(2))-H Activation 3.2Intramolecular C-Si Bond Formation through C(sp(3))-H Activation 4 Siloles Synthesis through Heteroannulation 5 C-Si Bond Formation through Remote C-H Activation 6 C-Si Bond Formation through C-O Bond Cleavage 7 Metal-Free Methods for C-Si Bond Formation 8 Summary and Outlook