期刊
NUCLEIC ACIDS RESEARCH
卷 43, 期 D1, 页码 D1171-D1175出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gku1193
关键词
-
资金
- EU- FP7 'INFRAFRONTIER- I3' [312325]
- European Molecular Biology Laboratory
- European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
- MRC [MC_UP_1502/2, MC_U142684172, MC_U142684171] Funding Source: UKRI
- Medical Research Council [MC_U142684172, MC_UP_1502/2] Funding Source: researchfish
The laboratory mouse is a key model organism to investigate mechanism and therapeutics of human disease. The number of targeted genetic mouse models of disease is growing rapidly due to high-throughput production strategies employed by the International Mouse Phenotyping Consortium (IMPC) and the development of new, more efficient genome engineering techniques such as CRISPR based systems. We have previously described the European Mouse Mutant Archive (EMMA) resource and how this international infrastructure provides archiving and distribution worldwide for mutant mouse strains. EMMA has since evolved into INFRAFRONTIER (http://www.infrafrontier.eu), the pan-European research infrastructure for the systemic phenotyping, archiving and distribution of mouse disease models. Here we describe new features including improved search for mouse strains, support for new embryonic stem cell resources, access to training materials via a comprehensive knowledgebase and the promotion of innovative analytical and diagnostic techniques.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据