期刊
NUCLEIC ACIDS RESEARCH
卷 43, 期 D1, 页码 D1057-D1063出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gku1113
关键词
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资金
- National Human Genome Research Institute of the National Institutes of Health [U41HG006104, U41HG007822, U41HG002273]
- National Institutes of Health
- British Heart Foundation [RG/13/5/30112]
- Parkinson's UK [G-1307]
- European Molecular Biology Laboratory (EMBL)
- EMBL
- British Heart Foundation [RG/13/5/30112] Funding Source: researchfish
- Parkinson's UK [G-1307] Funding Source: researchfish
The Gene Ontology Annotation (GOA) resource ( ext-link-type=uri xlink:href=http://www.ebi.ac.uk/GOA xlink:type=simple>http://www.ebi.ac.uk/GOA) provides evidence-based Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB). Manual annotations provided by UniProt curators are supplemented by manual and automatic annotations from model organism databases and specialist annotation groups. GOA currently supplies 368 million GO annotations to almost 54 million proteins in more than 480 000 taxonomic groups. The resource now provides annotations to five times the number of proteins it did 4 years ago. As a member of the GO Consortium, we adhere to the most up-to-date Consortium-agreed annotation guidelines via the use of quality control checks that ensures that the GOA resource supplies high-quality functional information to proteins from a wide range of species. Annotations from GOA are freely available and are accessible through a powerful web browser as well as a variety of annotation file formats.
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