3,5-Disubstituted 2-Aminopyridines via Nickel-Catalyzed Cyclo-addition of Terminal Alkynes and Cyanamides

The regioselectivity of the Ni/SIPr-catalyzed cyc addition terminal alkynes and cyanamides was explored. In general, 3,5-disubstituted 2-aminopyridines were formed as the major product.