相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks
Ryan Kuhar et al.
NUCLEIC ACIDS RESEARCH (2014)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2013)
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
Maarten Holkers et al.
NUCLEIC ACIDS RESEARCH (2013)
CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
Thomas J. Cradick et al.
NUCLEIC ACIDS RESEARCH (2013)
High Frequency Targeted Mutagenesis Using Engineered Endonucleases and DNA-End Processing Enzymes
Fabien Delacote et al.
PLOS ONE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR
Hiroki Torikai et al.
BLOOD (2012)
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
Haishan Gao et al.
CELL RESEARCH (2012)
FLASH assembly of TALENs for high-throughput genome editing
Deepak Reyon et al.
NATURE BIOTECHNOLOGY (2012)
Gene-editing nucleases
Monya Baker
NATURE METHODS (2012)
Gene editing: not just for translation anymore
Moira A. McMahon et al.
NATURE METHODS (2012)
Coupling endonucleases with DNA end-processing enzymes to drive gene disruption
Michael T. Certo et al.
NATURE METHODS (2012)
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
Sarah Baxter et al.
NUCLEIC ACIDS RESEARCH (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders
Blythe D. Sather et al.
MOLECULAR THERAPY (2011)
A TALE nuclease architecture for efficient genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2011)
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
Feng Zhang et al.
NATURE BIOTECHNOLOGY (2011)
An unbiased genome-wide analysis of zinc-finger nuclease specificity
Richard Gabriel et al.
NATURE BIOTECHNOLOGY (2011)
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)
Jeffry D. Sander et al.
NATURE METHODS (2011)
Tracking genome engineering outcome at individual DNA breakpoints
Michael T. Certo et al.
NATURE METHODS (2011)
Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
Vikram Pattanayak et al.
NATURE METHODS (2011)
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
Ting Li et al.
NUCLEIC ACIDS RESEARCH (2011)
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak et al.
NUCLEIC ACIDS RESEARCH (2011)
Tapping natural reservoirs of homing endonucleases for targeted gene modification
Ryo Takeuchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification
Barry L. Stoddard
STRUCTURE (2011)
The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation
Aaron Klug
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
Michael R. Lieber
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
Michelle Christian et al.
GENETICS (2010)
Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion
Cem Soellue et al.
NUCLEIC ACIDS RESEARCH (2010)
Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs
Justin Ashworth et al.
NUCLEIC ACIDS RESEARCH (2010)
Exploitation of binding energy for catalysis and design
Summer B. Thyme et al.
NATURE (2009)
Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation
Ryo Takeuchi et al.
NUCLEIC ACIDS RESEARCH (2009)
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display
Jordan Jarjour et al.
NUCLEIC ACIDS RESEARCH (2009)
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
Jens Boch et al.
SCIENCE (2009)
A Simple Cipher Governs DNA Recognition by TAL Effectors
Matthew J. Moscou et al.
SCIENCE (2009)
Rapid Open-Source engineering of customized zinc-finger nucleases for highly efficient gene modification
Morgan L. Maeder et al.
MOLECULAR CELL (2008)
DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger Nucleases
Tatjana I. Cornu et al.
MOLECULAR THERAPY (2008)
Regulation of DNA double-strand break repair pathway choice
Meena Shrivastav et al.
CELL RESEARCH (2008)
Meganucleases and DNA double-strand break-induced recombination:: Perspectives for gene therapy
Frederic Paques et al.
CURRENT GENE THERAPY (2007)
Zinc finger tools: custom DNA-binding domains for transcription factors and nucleases
Jeffrey G. Mandell et al.
NUCLEIC ACIDS RESEARCH (2006)
BLAT - The BLAST-like alignment tool
WJ Kent
GENOME RESEARCH (2002)
分享论文
