期刊
NUCLEIC ACIDS RESEARCH
卷 41, 期 D1, 页码 D996-D1008出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gks1042
关键词
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资金
- Department of Health and Human Services Resources and Services [1C76HF15069-01-00, 1C76HF19619-01-00]
- National Institute of Mental Health [RC2MH089921, RC2MH090047, RC2MH089929, HHSN-271-2008-0047]
- Ivy Glioblastoma Atlas Project
- ALS Association
- PVA Research Foundation
- Wyeth Research
- PEMCO Insurance
- National Multiple Sclerosis Society
- International Spinal Research Trust
- Department of Defense USAMRAA [W81XWH-06-1-0131]
- National Institutes of Health [RO1 HL59658]
- Allen Institute for Brain Science
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL059658] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [RC2MH089921, RC2MH089929, RC2MH090047] Funding Source: NIH RePORTER
The Allen Brain Atlas (http://www.brain-map.org) provides a unique online public resource integrating extensive gene expression data, connectivity data and neuroanatomical information with powerful search and viewing tools for the adult and developing brain in mouse, human and non-human primate. Here, we review the resources available at the Allen Brain Atlas, describing each product and data type [such as in situ hybridization (ISH) and supporting histology, microarray, RNA sequencing, reference atlases, projection mapping and magnetic resonance imaging]. In addition, standardized and unique features in the web applications are described that enable users to search and mine the various data sets. Features include both simple and sophisticated methods for gene searches, colorimetric and fluorescent ISH image viewers, graphical displays of ISH, microarray and RNA sequencing data, Brain Explorer software for 3D navigation of anatomy and gene expression, and an interactive reference atlas viewer. In addition, cross data set searches enable users to query multiple Allen Brain Atlas data sets simultaneously. All of the Allen Brain Atlas resources can be accessed through the Allen Brain Atlas data portal.
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