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Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN
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Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
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Bloom DNA Helicase Facilitates Homologous Recombination between Diverged Homologous Sequences
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Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
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The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
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Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions
Anthony J. Cesare et al.
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Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation
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BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
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Role for BLM in replication-fork restart and suppression of origin firing after replicative stress
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Anaphase onset before complete DNA replication with intact checkpoint responses
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PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint
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Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
K Paeschke et al.
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POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
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Shelterin: the protein complex that shapes and safeguards human telomeres
T de Lange
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Telomere shortening exposes functions for the mouse Werner and bloom syndrome genes
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Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2
K Lillard-Wetherell et al.
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BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks
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Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
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Essential role of limiting telomeres in the pathogenesis of Werner syndrome
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Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells
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DNA damage foci at dysfunctional telomeres
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The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis
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Telomere maintenance by recombination in human cells
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The Bloom's syndrome gene product promotes branch migration of Holliday junctions
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Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
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Nuclear structure in normal and Bloom syndrome cells
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The Bloom's syndrome gene product interacts with topoisomerase III
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