4.8 Article

From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Molecular modeling study of intercalation complexes of tricyclic carboxamides with d(CCGGCGCCGG)2 and d(CGCGAATTCGCG)2

Athanasia Varvaresou et al.

JOURNAL OF MOLECULAR MODELING (2011)

Article Multidisciplinary Sciences

In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models

Amparo Garcia-Lopez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biochemistry & Molecular Biology

Myotonic dystrophy mouse models: towards rational therapy development

Mario Gomes-Pereira et al.

TRENDS IN MOLECULAR MEDICINE (2011)

Review Biochemistry & Molecular Biology

Drug-target residence time: critical information for lead optimization

Hao Lu et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Grading the commercial optical biosensor literature-Class of 2008: 'The Mighty Binders'

Rebecca L. Rich et al.

JOURNAL OF MOLECULAR RECOGNITION (2010)

Article Biochemistry & Molecular Biology

Rational and Modular Design of Potent Ligands Targeting the RNA That Causes Myotonic Dystrophy 2

Melissa M. Lee et al.

ACS CHEMICAL BIOLOGY (2009)

Article Biochemical Research Methods

A global benchmark study using affinity-based biosensors

Rebecca L. Rich et al.

ANALYTICAL BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy

Agnieszka Kiliszek et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding

Jonathan F. Arambula et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Pentamidine reverses the splicing defects associated with myotonic dystrophy

M. Bryan Warf et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA

Thurman M. Wheeler et al.

SCIENCE (2009)

Review Chemistry, Multidisciplinary

Targeting RNA with small molecules

Jason R. Thomas et al.

CHEMICAL REVIEWS (2008)

Review Clinical Neurology

Myotonic dystrophy: Therapeutic strategies for the future

Thurman M. Wheeler

NEUROTHERAPEUTICS (2008)

Article Biochemistry & Molecular Biology

Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs

Yuan Yuan et al.

NUCLEIC ACIDS RESEARCH (2007)

Review Biochemistry & Molecular Biology

RNA-dominant diseases

Robert J. Osborne et al.

HUMAN MOLECULAR GENETICS (2006)

Review Chemistry, Multidisciplinary

Dynamic combinatorial chemistry

Peter T. Corbett et al.

CHEMICAL REVIEWS (2006)

Article Biotechnology & Applied Microbiology

Opinion - Drug-target residence time and its implications for lead optimization

Robert A. Copeland et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Biochemistry & Molecular Biology

Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

Xiaoyan Lin et al.

HUMAN MOLECULAR GENETICS (2006)

Article Biochemical Research Methods

Kinetic analysis of a high-affinity antibody/antigen interaction performed by multiple Biacore users

Phinikoula S. Katsamba et al.

ANALYTICAL BIOCHEMISTRY (2006)

Article Chemistry, Organic

Resin-bound dynamic combinatorial chemistry

BR McNaughton et al.

ORGANIC LETTERS (2006)

Review Pharmacology & Pharmacy

Natural antisense and noncoding RNA transcripts as potential drug targets

Claes Wahlestedt

DRUG DISCOVERY TODAY (2006)

Article Multidisciplinary Sciences

The structural basis of myotonic dystrophy from the crystal structure of CUG repeats

BHM Mooers et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Genetics & Heredity

Diseases of unstable repeat expansion: Mechanisms and common principles

JR Gatchel et al.

NATURE REVIEWS GENETICS (2005)

Review Clinical Neurology

Clinical and molecular aspects of the myotonic dystrophies: A review

L Machuca-Tzili et al.

MUSCLE & NERVE (2005)

Article Chemistry, Organic

A mild and efficient one-step synthesis of quinolines

BR McNaughton et al.

ORGANIC LETTERS (2003)

Article Biochemistry & Molecular Biology

Solution structure of the HIV-1 frameshift inducing stem-loop RNA

DW Staple et al.

NUCLEIC ACIDS RESEARCH (2003)

Review Infectious Diseases

Acridine - a neglected antibacterial chromophore

M Wainwright

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2001)

Article Multidisciplinary Sciences

Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat

A Mankodi et al.

SCIENCE (2000)